The popularity of taking “shrooms” is increasing all over the Western world. Science is looking into the health benefits mainly for people with mental health disorders but is also looking at the lasting positive effects on healthy people. The potential positive effects on personal development are enormous. And then there are the additional use cases of microdosing and the recreational use of psychedelics. So the question of “What is the best way to take mushrooms?” is a valid one. Below, we will talk about the do’s and don'ts. What should be avoided and what should always be taken into consideration?
With all the benefits being advertised and articles being published, it can almost feel like shrooms are good for everything. And while the benefits and science are valid, psilocybin, the active ingredient in magic mushrooms, is not a substance that should be taken lightly. Science shows us 67% of the participants put their experience with psychedelics in their top 5 of most valuable experiences1, but only when done right. Bad trips are a fact, so first we’ll give you some absolute “don’ts” when taking magic mushrooms before we look at some of the best practices when taking magic mushrooms.
Don’t mix magic mushrooms with other drugs (or medicine). This includes alcohol. Even the use of caffeine can have a strong effect on the trip so we always recommend not drinking coffee. Mixing with cannabis can lead to paranoia. Combining these substances with hard drugs such as cocaine, MDMA or other, similar drugs can lead to a feeling of being overwhelmed. And don’t mix with other psychedelic substances such as ayahuasca, LSD or 2CB. The effect is similar but the dosing of the substances becomes close to impossible as it is uncertain how these drugs interact. In short; you should understand that a part of tripping is the intensification and amplification of feelings, emotions and thought patterns. To yield the most benefits and avoid a negative or unnecessary confusing experience, the best way is to experience these in a clear way. Trust us; taking the magic mushrooms without any other substance is more than enough to have the experience of a lifetime.
Another important practical “don’t” is taking magic mushrooms at a location that is unsafe. So no busy roads, high buildings, cliffs, deep water, wild animals, etc. Tripping, even done perfectly right, can sometimes be pretty confusing. An external danger or even an external fear of a possible danger definitely won’t help. It could unintentionally change an overwhelming situation to a fearful situation, and a fearful situation to a dangerous situation. Being in a trusting and physically safe environment will benefit your trip the most.
Last but not least. Psychedelics are not for everybody, and even when it is for you, it should not be taken without the right considerations. Awayk uses strict selection criteria and so should you. We use this to ensure a participant will benefit from the experience and the experience won’t form a threat to their own well-being. Our Participant Agreement provides a clear overview. They use the same list in clinical trials, but we added some considerations based on our experience. It lists all the mental conditions, medicine use, family history and past traumas we think should exclude someone from taking a psychedelic substance. If after reading you have any doubts, questions or concerns, please reach out. We are here to help, even if you are nowhere near considering an Awayk journey.
Here we will focus on various aspects that are to be taken into account when taking magic mushrooms. The information provided applies to using psychedelics for personal development. This will not (always) apply to microdosing. To learn more about microdosing read our blogpost on microdosing. We will cover:
For any psychedelic journey that is aimed at personal development, having a guide to support you will make all the difference. From preparation through integration, they will be there for you to help you make the most out of it. A good guide should:
The "set" refers to the mindset, expectations, and psychological state of the individual embarking on a psychedelic journey. A person's inner landscape plays a pivotal role in shaping the experience; it is vital to cultivate openness and respect for the substances. “Tripping” involves introspection and self-reflection, clarifying of your motivations, and acknowledging fears or anxieties that may arise. The right mindset is one of curiosity, openness, embrace and without judgment. Like a young kid who is discovering new things.
A good guide will help you create the right mindset, by simply talking about your current and desired mindset, or by using breathing exercises or guided meditations
The setting entails your physical, emotional and social surroundings. Creating a safe and supportive setting is essential for optimising the experience and mitigating potential risks. The surroundings should be comfortable, have the correct type of music, dim lighting and access to nature and support if needed.
There should be no sudden disturbance possible. Start early, so you are not pressured to finish in time. A guide should give you a sense of a safe haven, granting you the permission to really let go of the intention to stay in control.
If it is a group setting, make sure you trust each other wholeheartedly and feel comfortable enough around them to cry or be angry, laugh out loud or be silent. A good set, setting and guide, are enough to make a safe and deep trip. Keep reading if you want to know how you can maximise the actual benefits of taking shrooms.
Scientific studies, such as "Carhart-Harris, R. L. et al (2018): Psychedelics and the essential importance of context" and "Cavarra, M. et al (2022): Psychedelic-Assisted Psychotherapy—A Systematic Review" strongly support and emphasise the role of preparation and integration. At Awayk, we double down on our preparation phase. Good preparation reduces anxiety, builds trust, fosters a positive mindset before taking the mushrooms, and provides tools for navigating the experience. This leads to a more profound and meaningful experience and significantly lowers the chances of having a “bad trip.” Read more about our preparation here.
The dosage of shrooms plays a critical role in shaping the intensity and duration of the experience. Too high a dose and things might get scary. Plus, most of the benefits occur in the subconscious, so it might be difficult to recall their experience. Too low a dose and one will not exceed the journey threshold and receive limited value from the trip. Contrary to what many think, dosing has little to do with gender or body weight. Instead, it depends on the desire for control and the rigidity of ego structure. If someone can fully surrender, they are more likely to have a full-blown experience on a lower dose. Read more about set, setting and dosage here.
Proper and thoughtful integration supports lasting positive changes by helping individuals make sense of their journey's insights and apply them to their daily lives. Integration bridges the insights gained during a psychedelic journey and their meaningful integration into everyday life. They should help to relive the insightful feeling daily, to enable and hold a more conscious mind and let small changes happen. We consider four ingredients crucial for optimising these positive sustainable changes. Read our full blog about integration here to learn more.
Taking magic mushrooms can result in it being one of the most impactful things you will ever do. But it does depend on doing it right. Bad trips are real, but can also be managed if set, setting and dosage are being controlled. here is one other thing to be considered though; always do your own research, like you are doing now. Be open and sceptical at the same time. There is a lot of information out there, and while most of it is correct and meant well, we have also seen false information. When in doubt, feel free to drop us a line. We are here for you.
Interested in a psychedelic retreat? Contact us.
Understanding how long magic mushrooms remain in our system depends on how you look at it. In short, magic mushrooms are traceable in our bodies for about 24 hours. The visual and mental effects of psychedelics - what we call the “trip” - typically last between 4 and 6 hours1. Then there is the after-effect of increased neuroplasticity which can persist for 1-3 weeks2. The positive effects of the trip, with increased focus, awareness, creativity, empathy, and more, can last a lifetime.
Want to know more about the different factors which influence how long magic mushrooms stay on your systems? We are proud to say that we have, by now, guided many different trips for different individuals. We have written down our findings below.
Dosage will impact the duration of a trip. For a small dose, the effects will seem to ware of sooner (total time 3-5 hours) while a high dose will last a bit longer (4-6 hours). But be aware; unlike many substances, magic mushrooms can't be dosed solely based on body weight. Every individual reacts uniquely to a dose. This is still a big misconception that not many people seem to be aware of.
A small dose might have a bit impact on someone who finds it easy to ‘let go’ and ‘dive deep’. On the other hand, someone that is often caught up in thinking and finds it hard to let go of those thinking patterns, will require a higher dose in order to have the same effects. In our preparation process, we will talk about those topics to find out what the right dosage will be. We also employ a breathwork session to better understand the participants' readiness to ‘let go’ and fully immerse themselves. Lastly, we make use of a booster schedule.
We follow a booster schedule where we start with a moderate dose. After an hour, we can re-dose based on the participants' responses to the first dosage. Dosage matters significantly; while a low dose might yield a 3.5-hour trip, a higher dose can extend the experience to 6 hours or more. Interestingly, research suggests that higher doses lead to deeper insights and more meaningful and insightful experiences3.
The intensity of the trip also depends on 'set' and 'setting'. 'Set' refers to mindset; psychedelics amplify emotions, so mental preparedness is crucial. At Awayk, we prioritise intention setting, and we train participants on how to let go and build a mindset of curiosity and openness. ‘Setting' refers to the external environment and atmosphere, such as the people involved and the location's atmosphere and surroundings. Choosing a serene location, such as a forest house with minimal distractions, enhances the experience. Read more about set and setting, preparation and integration to fully understand their importance.
Before delving into the duration of the effects, let's explore the trip's onset. It typically begins 15 minutes to half an hour after ingestion and is characterised by fluctuating waves of effects. As time elapses, these waves intensify, reaching a peak within an hour. You'll linger at this peak for about an hour before the effects gradually subside over 2 to 4 hours, resulting in a 4 to 6-hour total4.
So, in summary, an average trip on shrooms lasts 4-6 hours, but we don’t recommend driving home afterwards. While the psilocybin, the active component in magic mushrooms, may not be active in your system anymore it will still take time to digest what has been experienced. We always encourage participants to get a head start with integration, so now is a great time to write down the biggest insights or to speak to your guide about the many things that you have experienced.
After 24 hours, the magic mushroom is undetectable in your system. However, the positive effects persist. A trip can bring many new insights that enable a person to look forward to the next phase of their life. And for about three weeks, the brain is experiencing a renewed capability to learn new things, thanks to neuroplasticity. Neuroplasticity is the formation of new neural connections during and after the trip5. Often, change is hard for people, as we like to follow old patterns and hence it is hard to create new pathways. Neuroplasticity changes this fact as it actually allows new connections in the brain. This is partly why psychedelics can be so powerful; they help create real insights and at the same time, neurologically they enable a person to integrate desired changes into daily life! This lasts for around 3 weeks and gives room to create lasting changes in behaviour and thought patterns.
With a well-planned and well-guided integration process, these changes may last a lifetime!
Interested in a psychedelic retreat? See our program here.
Begrijpen hoe lang magic truffels in ons systeem blijven, hangt af van hoe je het bekijkt. Kort door de bocht zijn magic truffels ongeveer 24 uur detecteerbaar in ons bloed1. De visuele en mentale effecten van psychedelica - wat we de “trip” noemen - duren meestal tussen de 4 en 6 uur en de piek meestal ongeveer een uur2. Echter is de perceptie van deze duur weer een ander verhaal. Dan is er nog het na-effect van verhoogde neuroplasticiteit, dat 1-3 weken kan aanhouden. Als slot kunnen de positieve effecten van de trip, zoals verhoogde focus, bewustzijn, creativiteit, empathie en meer, een leven lang meegaan.
De dosering zal de duur van een trip beïnvloeden. Voor een kleine dosis zullen de effecten sneller lijken af te nemen (totale tijd 3-5 uur), terwijl een hoge dosis iets langer zal duren (4-6 uur). Belangrijk om te weten; in tegenstelling tot veel andere stoffen kunnen magic truffels niet uitsluitend op basis van lichaamsgewicht worden gedoseerd. Elke persoon reageert uniek op een dosis. Dit is nog steeds een groot misverstand.
Een kleine dosis van magic truffels kan een grote impact hebben op iemand die het gemakkelijk vindt om 'los te laten' en 'diep te duiken'. Aan de andere kant zal iemand die vaak in gedachten verzonken is en het moeilijk vindt om deze denkpatronen los te laten, een hogere dosis nodig hebben om dezelfde effecten te ervaren. In ons voorbereidingsproces bespreken we deze onderwerpen om te bepalen wat de juiste dosering zal zijn. We gebruiken ook een ademwerk sessie om beter te begrijpen hoe goed de deelnemers zich kunnen overgeven en zich volledig kunnen onderdompelen. Ten slotte maken we gebruik van een booster schema.
Boosterschema
Met Awayk volgen we een booster schema waarbij we beginnen met een gematigde dosis. Na een uur kunnen we opnieuw doseren op basis van de reacties van de deelnemers op de eerste dosering. Dosering is van groot belang; terwijl een lage dosis een trip van 3,5 uur kan opleveren, kan een hogere dosis de ervaring verlengen tot 6 uur of meer. Interessant is dat onderzoek suggereert dat een hogere dosis leidt tot diepere inzichten en meer betekenisvolle ervaringen3.
De intensiteit van de trip hangt ook af van 'set' en 'setting'. 'Set' verwijst naar de mindset; psychedelica versterken emoties, dus mentale voorbereiding is cruciaal. Bij Awayk geven we prioriteit aan het stellen van intenties en trainen we deelnemers om los te laten en een mindset van nieuwsgierigheid en openheid op te bouwen. 'Setting' verwijst naar de externe omgeving en sfeer, zoals de betrokken mensen en de sfeer en omgeving van de locatie. Het kiezen van een serene locatie, zoals een bos met minimale afleidingen, verbetert de ervaring van de magic truffels. Lees verder over set and setting, voorbereiding en integratie om het belang hiervan beter te begrijpen.
Laten we, voordat we verder ingaan op de duur van de effecten, eerst het eerste deel van de trip verkennen. Deze begint meestal 15 minuten tot een half uur na inname en wordt gekenmerkt door hetn opkomen van de psychedelica, wat meestal gebeurt in golven. Naarmate de tijd verstrijkt, worden deze golven intenser en bereiken ze een piek na ongeveer een uur. Je blijft ongeveer een uur op deze piek voordat de effecten geleidelijk afnemen over 2 tot 4 uur, wat resulteert in een totale duur van 4 tot 6 uur.
Een gemiddelde trip op magic truffels of mushrooms duurt 4-6 uur, maar we raden niet aan om daarna direct naar huis te rijden. Hoewel de psilocybine, het actieve bestanddeel in magic truffels, misschien niet meer actief is in je systeem, zal het nog tijd kosten om te verwerken wat je hebt ervaren. We moedigen deelnemers altijd aan om te beginnen met de integratie; nu is het een goed moment om de grootste inzichten op te schrijven of met je gids te praten over de vele dingen die je hebt ervaren4.
Na 24 uur is de magic truffels ondetecteerbaar in je systeem. De positieve effecten blijven echter bestaan. Een trip kan veel nieuwe inzichten brengen die een persoon in staat stellen uit te kijken naar de volgende fase van hun leven. En gedurende ongeveer drie weken ervaart de hersenen een vernieuwd vermogen om nieuwe dingen te leren dankzij neuroplasticiteit. Neuroplasticiteit is de vorming van nieuwe neurale verbindingen tijdens en na de trip5. Vaak is verandering moeilijk voor mensen omdat we graag oude patronen volgen en het daarom moeilijk is om nieuwe paden te creëren. Neuroplasticiteit verandert dit feit omdat het daadwerkelijk nieuwe verbindingen in de hersenen mogelijk maakt. Dit is gedeeltelijk waarom psychedelica zo krachtig kunnen zijn; ze helpen echte inzichten te creëren en tegelijkertijd neurologisch in staat stellen om gewenste veranderingen in het dagelijks leven te integreren! Dit duurt ongeveer 3 weken en biedt ruimte om blijvende veranderingen in gedrag en denkpatronen te creëren.
Met een goed gepland en goed begeleid integratieproces kunnen deze veranderingen een leven lang meegaan!
Mocht je nog vragen hebben na aanleiding van deze blog, neem gemakkelijk vrijblijvend contact met ons op. Daar zijn we voor!
Psychedelics are in fashion and microdosing magic mushrooms is an integral part of the psychedelic renaissance. Microdosing is a method of consuming sub-threshold amounts of substances like magic mushrooms to enhance creativity, productivity, and emotional balance, without experiencing the full-blown psychedelic visual and bodily effects. This practice has gained popularity thanks to pioneers like Paul Stamets, James Fadiman, and even Albert Hofmann, the inventor of LSD, who lived to be 103 years old. But what exactly is microdosing, and why are people drawn to it?
Microdosing involves taking a small dose of a psychedelic substance—typically 1/20 to 1/10 of a recreational dose - so little that you don't experience an intense trip and/or alterations in consciousness, but enough to make you feel sharper, more empathetic, more creative, or just happier. This has become a trend in places like Silicon Valley because people believe it helps them perform better at work and in their private lives. Although scientists are still conducting extensive research on it, many people swear by the benefits of microdosing magic mushrooms in their daily lives.
The immediate effects of microdosing vary per individual and depend on dosage and substance. LSD and Psilocybin - as found in magic mushrooms, are two of the most popular choices. Not a lot of research is available on microdosing yet, but going with our own experience, which correlates with what most other users report, the effects usually last about two days. On the first day, the immediate effects such as increased focus, creativity, tranquillity, and mindfulness are most tangible. On the second day, however, one usually still feels what we call an ‘afterglow’. During this period it is common to feel more grounded, and a general sense of tranquillity and mindfulness can still be felt. This afterglow is the reason why most people use the following rhythm, commonly known as the Fadiman Protocol;
Day 1: 1st microdosing day
Day 2: Transition day
Day 3: Normal day / Rest day
Day 4: 2nd microdosing day
Day 5: Transition day
Day 6: Normal day / Rest day
Please note that LSD is illegal in most countries, while Magic Truffles are legal in countries like The Netherlands and hence can offer a more accessible option.
Research and anecdotal evidence, including insights from neuroscientist Andrew Huberman, suggest that the benefits of microdosing magic mushrooms may sometimes overlap with placebo effects. We see an increase in empathy, focus, energy, creativity, emotional well-being and problem-solving So despite the debate over the placebo effect, the personal and anecdotal benefits cited by many underscore a valuable impact on their lives.
We do believe, and see in our environment, that the effects of microdosing are usually stronger felt by users who have experienced a high dose of psychedelics once. Microdosing, for example with magic mushrooms, creates a subtle change in our conditioned consciousness, which allows us to be more focused, emphatic, mindfull, etc. A high dose of psychedelics does the same but to a much stronger effect. We believe that people who have experienced the effects of a high dose of psychedelics can better recognize, and lean into, the effects of a smaller dose.
Ok, this is going to be a bit technical, as we are going to explain how psychedelics works from a neurologic perspective. But hey, we like to understand how things work ourselves, so this is for the like-minded geeks :-).
Microdosing psychedelics such as LSD and psilocybin primarily influence the brain's serotonergic system by targeting the serotonin 5-HT2A receptors, which are crucial for modulating neuroplasticity - the brain's capacity to reorganize and form new neural connections.
The interaction with 5-HT2A receptors triggers a cascade of neurochemical activities, including the release of brain-derived neurotrophic factor (BDNF), a protein integral to the growth, maintenance, and survival of neurons. BDNF's role in neuroplasticity is well-documented, with increases in BDNF correlated with improved learning and memory capabilities. Additionally, psychedelics initiate a surge in glutamate release, an excitatory neurotransmitter that facilitates synaptic plasticity, the foundation of learning and memory. This glutamate release is thought to contribute to the cognitive enhancements reported by individuals who microdose, enabling a state of heightened learning and problem-solving ability. All of the aforementioned has been proven for higher doses of psychedelics. Research has shown that Many animal studies investigating chronic dosing have not differentiated between microdoses and hallucinogenic doses, which may be an important distinction. However, more research is required to better understand the dynamics.
Moreover, the psychological effects of microdosing magic mushrooms, such as increased emotional balance and enhanced creativity, can also be attributed to these neurobiological changes. The adaptive neural environment fostered by microdosing may help dismantle rigid thought patterns and behaviours, offering a novel perspective for ‘healthy individuals’ as well as for those suffering from conditions such as depression and anxiety.
By bolstering the brain's plasticity and promoting the health of neural networks, microdosing with psychedelics presents a compelling avenue for research into non-traditional psychiatric treatments. The potential for lasting changes in brain function and structure through such minimal interventions is a specific area of research interest.
Both personal anecdotes and scientific research contribute to our understanding of microdosing's benefits. Whether it's enhancing creative output, improving mental health, or simply adding a subtle uplift to one’s day-to-day life, the practice continues to attract interest and debate.
As microdosing magic mushrooms continues to gain popularity, it's clear that this practice offers a unique pathway for individuals seeking to enhance their mental and emotional well-being. Whether through the subtle shifts in perception, it provides or the more profound personal insights users report, microdosing stands at the intersection of ancient wisdom and modern science, offering a nuanced tool for personal development and well-being.
Having experienced this ourselves we created our own microdosis best practices based on the Fadiman findings, and are happy to share the protocol with you. If you would like to put this into practice, don’t hesitate to get in touch! While we don’t sell microdoses, we would love to explain the practicalities and pros and cons in more details before you embark on this journey.
Interested in a psychedelic retreat? See our program here.
Much of this post is based on scientific research. If you would enjoy learning in more depth about microdosing magic mushrooms we invite you to start here:
Psychedelica lijken helemaal in de mode te zijn en microdosing magic mushrooms is inmiddels een integraal onderdeel van de psychedelische renaissance. Microdosing is een methode waarbij kleine hoeveelheden van stoffen zoals truffels worden ingenomen om creativiteit, productiviteit en emotionele balans te verbeteren, zonder de volledige psychedelische visuele en lichamelijke effecten te ervaren. Dit is populair geworden dankzij pioniers zoals Paul Stamets, James Fadiman, en zelfs Albert Hofmann, de uitvinder van LSD, die 103 jaar oud werd. Maar wat is microdosing truffels precies, en waarom voelen mensen zich erdoor aangetrokken?
Microdosing houdt in dat je een kleine dosis van een psychedelische stof neemt—typisch 1/20 tot 1/10 van een “normale” dosis; zo weinig dat je geen intense trip en/of veranderingen in bewustzijn ervaart, maar genoeg om je scherper, empathischer, creatiever of gewoon gelukkiger te voelen. Dit is een trend geworden in plaatsen zoals Silicon Valley omdat mensen geloven dat het hen helpt beter te presteren op het werk en in hun privéleven. Hoewel wetenschappers nog uitgebreid onderzoek doen en de effecten niet bewezen achten, zweren veel mensen bij de voordelen van microdosing magic mushrooms in hun dagelijks leven.
De directe effecten van microdosing variëren per individu en zijn afhankelijk van de dosering en de stof. LSD en psilocybine, de laatste van de twee zoals gevonden in magic mushrooms en truffels, zijn de twee meest gangbare keuzes. Er is nog niet veel onderzoek beschikbaar over microdosing truffels, maar op basis van onze eigen ervaring, die overeenkomt met wat de meeste andere gebruikers melden, duren de effecten meestal ongeveer twee dagen. Op de eerste dag zijn de directe effecten zoals verhoogde focus, creativiteit, kalmte en mindfulness het meest tastbaar. Op de tweede dag voelt men echter meestal nog wat we een 'afterglow' noemen. Gedurende deze periode is het gebruikelijk om je meer geaard te voelen en een algemeen gevoel van kalmte en mindfulness te ervaren. Deze afterglow is de reden waarom de meeste mensen het volgende ritme gebruiken, algemeen bekend als het Fadiman Protocol.
Dag 1: 1e microdosing dag
Dag 2: Overgangsdag
Dag 3: Normale dag / Rustdag
Dag 4: 2e microdosing dag
Dag 5: Overgangsdag
Dag 6: Normale dag / Rustdag
Let op dat LSD illegaal is in de meeste landen, terwijl magic truffels legaal zijn in landen zoals Nederland en dus een meer toegankelijke optie kunnen bieden.
Onderzoek en anekdotisch bewijs, waaronder inzichten van neurowetenschapper Andrew Huberman, suggereren dat de voordelen van microdosing truffels kunnen overlappen met placebo-effecten. We zien een toename in empathie, focus, energie, creativiteit, emotioneel welzijn en probleemoplossend vermogen. Ondanks de discussie over het placebo-effect benadrukken de persoonlijke en anekdotische voordelen die door velen worden genoemd de waardevolle impact op hun leven.
Wij geloven, en zien in onze omgeving, dat de effecten van microdosing meestal sterker worden gevoeld door gebruikers die ooit een hoge dosis psychedelica hebben ervaren. Microdosing, bijvoorbeeld met truffels, veroorzaakt een subtiele verandering in ons geconditioneerde bewustzijn, waardoor we ons meer kunnen focussen, empathischer, mindful, enz. Een hoge dosis psychedelica doet hetzelfde, maar met een veel sterker effect. We geloven dat mensen die de effecten van een hoge dosis psychedelica hebben ervaren, de effecten van een kleinere dosis beter kunnen herkennen en benutten.
Oké, dit wordt een beetje technisch, omdat we gaan uitleggen hoe psychedelica werkt vanuit een neurologisch perspectief. Maar hé, we willen graag begrijpen hoe dingen werken, dus dit is voor de gelijkgestemde nerds :-).
Microdosing psychedelica zoals LSD en psilocybine beïnvloedt voornamelijk het serotonergische systeem van de hersenen door de serotonine 5-HT2A-receptoren te targeten, die cruciaal zijn voor het moduleren van neuroplasticiteit—het vermogen van de hersenen om zichzelf te reorganiseren en nieuwe neurale verbindingen te vormen.
De interactie met 5-HT2A-receptoren triggert een cascade van neurochemische activiteiten, waaronder de afgifte van brain-derived neurotrophic factor (BDNF), een eiwit dat essentieel is voor de groei, het onderhoud en het overleven van neuronen. De rol van BDNF in neuroplasticiteit is goed gedocumenteerd, met toenames in BDNF die gecorreleerd zijn met verbeterde leer- en geheugenvaardigheden. Bovendien initiëren psychedelica een toename in glutamaat afgifte, een exciterende neurotransmitter die synaptische plasticiteit faciliteert, de basis van leren en geheugen. Deze glutamaat afgifte wordt geacht bij te dragen aan de cognitieve verbeteringen die door individuen die microdoseren worden gerapporteerd, waardoor een staat van verhoogd leren en probleemoplossend vermogen mogelijk wordt. Al het bovenstaande is bewezen voor hogere doses psychedelica. Onderzoek heeft aangetoond dat veel dierstudies die chronische dosering onderzoeken geen onderscheid maken tussen microdoses en hallucinogene doses, wat een belangrijk onderscheid kan zijn. Er is echter meer onderzoek nodig om de dynamiek beter te begrijpen.
Bovendien kunnen de psychologische effecten van microdosing truffels, zoals verhoogde emotionele balans en verbeterde creativiteit, ook worden toegeschreven aan deze neurobiologische veranderingen. De adaptieve neurale omgeving die door microdosing wordt bevorderd, kan helpen starre gedachtepatronen en gedragingen te doorbreken, waardoor een nieuw perspectief wordt geboden voor 'gezonde individuen' evenals voor degenen die lijden aan aandoeningen zoals depressie en angst.
Door de plasticiteit van de hersenen te versterken en de gezondheid van neurale netwerken te bevorderen, biedt microdosing met psychedelica een boeiend onderzoeksterrein voor niet-traditionele psychiatrische behandelingen. Het potentieel voor blijvende veranderingen in hersenfunctie en structuur door dergelijke minimale interventies is een specifiek onderzoeksgebied van belang.
Zowel persoonlijke anekdotes als wetenschappelijk onderzoek dragen bij aan ons begrip van de voordelen van microdosing. Of het nu gaat om het verbeteren van creatieve output, het verbeteren van de geestelijke gezondheid, of gewoon het toevoegen van een subtiele opkikker aan het dagelijks leven, de praktijk blijft interesse en debat aantrekken.
Naarmate microdosing truffels steeds populairder wordt, is het duidelijk dat deze praktijk een unieke weg biedt voor individuen die hun mentale en emotionele welzijn willen verbeteren. Of het nu gaat om de subtiele verschuivingen in perceptie die het biedt of de meer diepgaande persoonlijke inzichten die gebruikers rapporteren, microdosing staat op het snijvlak van oude wijsheid en moderne wetenschap, en biedt een genuanceerd hulpmiddel voor persoonlijke ontwikkeling en welzijn.
Zelf hebben we dit ervaren en hebben we onze eigen microdosing best practices gecreëerd op basis van de bevindingen van Fadiman, en we delen het protocol graag met je. Als je dit in de praktijk wilt brengen, aarzel dan niet om contact op te nemen! Hoewel we geen microdoses verkopen, leggen we graag de praktische aspecten en voor- en nadelen in meer detail uit voordat je aan deze reis begint.
Benieuwd naar wat een psychedelische ervaring voor jou kan betekenen? Bekijk onze programma's hier.
Veel van deze post is gebaseerd op wetenschappelijk onderzoek. Als je graag meer details wil weten over microdosing truffels, nodigen we je uit om hier te beginnen:
Luisteren: Huberman Lab. Dr. Huberman is een neurowetenschapper met uitgebreide kennis over psychedelica. Zijn podcast over psilocybine is zeer interessant; "How Psilocybin Can Rewire Our Brain."
Lezen: The Psychedelic Explorer's Guide. Een zeer praktisch boek over hoe psychedelica in het algemeen werken, inclusief een uitgebreide uitleg over microdosing.
Kijken: Ted Talk van Joseph Rootman - Microdosing Psychedelics: Small is Big. Joseph Rootman is een promovendus in het klinische psychologieprogramma aan de Universiteit van British Columbia en voerde een grootschalige studie uit naar microdosing.
Ayahuasca has become for the psychedelic experiences what Jeep is for terrain vehicles and Luxaflex is for window blinders. Other, similar psychedelics exist, one of which is Psilocybin, as found in magic mushrooms and magic truffles.
Ayahuasca and psilocybin are both powerful psychedelics renowned for their profound effects on consciousness and potential for personal transformation. Despite their different origins and cultural backgrounds, they share similarities in how they interact with the brain, yet they also possess distinct characteristics that influence their physical effects, legality, and overall experience.
Both ayahuasca and psilocybin primarily exert their effects through the serotonin system. Ayahuasca's active compound, DMT, and psilocybin both bind to serotonin 2A receptors, which are believed to play a key role in their psychedelic effects. This interaction leads to altered perception, mood, and thought patterns, facilitating deep introspective experiences. Research suggests that these substances can enhance neural plasticity—making the brain more malleable and open to forming new connections and pathways, learning new things and allowing for significant shifts in perspective and behavior1.
While ayahuasca and psilocybin share similar neurological mechanisms, their impact on the body and the nature of their experiences can differ markedly. Ayahuasca is known for its intense physical effects, including nausea and vomiting, often referred to as purging. This purging is considered by many cultures and users as an integral part of the experience, symbolizing the release of negative emotions and energies. In contrast, psilocybin, particularly in the form of magic truffles, tends to have milder physical effects, making it a softer option for those concerned about the intense bodily reaction associated with ayahuasca.
The legal status of Ayahuasca varies worldwide, significantly affecting its accessibility. In many European countries, Ayahuasca is illegal due to its DMT content. However, in the Netherlands, magic truffles containing psilocybin are legal and readily available, offering a lawful alternative for those seeking psychedelic experiences. This legal distinction makes psilocybin truffles a popular choice in areas where Ayahuasca is not permitted.
When selecting a psychedelic retreat, it's crucial to consider how well it prepares participants and integrates their experiences. Proper preparation and integration are vital for reaching the core of the intended transformation and utilizing it positively. Lack of these elements can pose risks. Ayahuasca, like other psychedelics, can induce significant shifts in perception and understanding, which can be empowering and enriching. Without appropriate guidance, however, these shifts can also lead to confusion and depression. Our approach is informed by both experience and thorough research, emphasizing a personal touch aimed at achieving optimal results and comprehensive integration for lasting positive changes. Read more here about the strong influence set, setting and dosage have on the experience.
Despite these differences, both ayahuasca and psilocybin offer powerful opportunities for personal growth and transformation. The depth and intensity of the experience with either substance can vary widely, depending heavily on the dosage, setting, and individual psychology. Ayahuasca may offer a more intense and physically challenging experience, often accompanied by profound visionary and emotional revelations. Psilocybin, while potentially offering a gentler physical experience, can still facilitate deep psychological insights and emotional breakthroughs, particularly at higher doses.
Ultimately, the choice between ayahuasca and psilocybin—or whether to use psychedelics at all—depends on personal preferences, legal considerations, and the goals of the individual seeking transformation. Both substances provide avenues for exploring the mind, healing emotional wounds, and fostering a deeper connection with the self and your environment, albeit through different paths. Get in touch for any help with this decision.
The conversation surrounding psychedelics has gained significant momentum in recent years, sparking both excitement and concern. While there are legitimate fears based on real risks, many false myths persist. This article aims to clarify the difference between genuine concerns and myths, while also offering guidance on how to minimise legitimate risks when using psychedelics responsibly.
A "bad trip" refers to a challenging psychedelic experience that can range from mild anxiety to extreme paranoia and frightening hallucinations. These negative experiences often stem from a combination of poor preparation, the wrong setting, or an unsuitable mindset. The intensity of a bad trip can vary, and it can leave lasting psychological impacts if not managed properly. Bad trips are more likely to occur when individuals take psychedelics in an environment where they do not feel entirely safe or comfortable, or when they are mentally unprepared for the experience. Stress, unresolved trauma, or anxiety about the experience can intensify these reactions. The key to reducing the likelihood of a bad trip is proper preparation, a supportive environment, and knowing your mental state before the journey begins1.
Psychedelics alter perception and can cause significant distortions in how individuals perceive their surroundings. This can impair motor coordination and spatial awareness, potentially leading to accidents, falls, or injuries—especially in environments where external dangers like traffic, cliffs, or bodies of water are present2. Without a sober guide or trip sitter to ensure physical safety, individuals under the influence of psychedelics may not recognize dangerous situations or make clear decisions in their altered state.
For those with a personal or family history of certain mental health disorders—particularly those related to psychosis, schizophrenia, or bipolar disorder—psychedelics pose significant risks. Research indicates that psychedelics can exacerbate these conditions, potentially triggering episodes of psychosis or mania. Even in individuals without diagnosed mental health disorders, psychedelics can bring unresolved traumas or emotional issues to the surface, which, if not handled properly, can lead to emotional distress or confusion. It is critical that anyone with a mental health history consults a healthcare professional before engaging in psychedelic use.
Many people assume that the correct dosage of psychedelics is based on body weight, similar to other substances. However, with psychedelics, this is not the case. Dosage impacts the intensity of the experience more than other factors like weight or size, making it easy for inexperienced users to take too much, too quickly. A high dose can result in overwhelming hallucinations, panic, and confusion, while a low dose might lead to a less impactful experience that doesn’t fully engage the substance's potential for personal insight. Starting with a low, manageable dose is always advised, especially for those new to psychedelics.
A persistent myth is that psychedelics cause brain damage or create "holes" in the brain. This is scientifically unfounded. Studies show that classic psychedelics like psilocybin, LSD, and DMT do not cause brain damage3. On the contrary, research has demonstrated that psychedelics may actually promote neuroplasticity—the brain’s ability to form new neural connections, which can aid in healing from trauma, depression, or negative thought patterns.
Another myth surrounding psychedelics is their potential for addiction. In contrast to substances like opioids, alcohol, or stimulants, classic psychedelics like LSD, psilocybin, and mescaline have a very low risk of addiction. They do not create compulsive drug-seeking behavior and, in fact, are often described as having an anti-addictive effect due to the intense nature of the experience, which can lead to lasting insights that reduce the desire for repetitive use. In fact, psychedelics are being researched for their potential to help treat addictions to other substances like nicotine and alcohol.
The myth that one can get “stuck” in a trip indefinitely is largely exaggerated. While a small percentage of users may experience Hallucinogen Persisting Perception Disorder (HPPD), where visual disturbances persist after the trip, these cases are rare. The notion that a person could be permanently trapped in a psychedelic experience is a falsehood propagated by misinformation. When HPPD occurs, it typically resolves on its own, though support and therapeutic care can help manage symptoms.
One of the most important factors in ensuring a safe and positive psychedelic experience is controlling the "set" (mindset) and "setting" (environment). These two aspects have a profound impact on the nature of the trip. Having a calm, curious, and open mindset going into the experience is crucial for avoiding fear and paranoia. Equally important is ensuring that the physical setting is comfortable, safe, and free from potential hazards. Being surrounded by trusted individuals, especially a sober trip sitter, can greatly enhance the feeling of security, allowing the individual to fully explore the psychedelic experience without fear.
Dosage control is another essential factor. If uncertain, always start with a lower dose, especially for first-time users. Purchasing substances from reputable or licensed vendors ensures quality control, but if that’s not possible, finding a service to test the potency and purity of the substance is vital. Using a digital scale that measures to the nearest 0.01g ensures precise dosing, especially with substances like psilocybin mushrooms or truffles. It's always better to take less than too much, as the experience can always be intensified later but is hard to reverse once the substance is in your system.
Proper preparation is essential for any psychedelic journey. This involves mental and emotional readiness, understanding the effects of the substance, and having tools such as breathing exercises, grounding techniques, and an open, curious mindset. A well-prepared individual is more likely to have a positive, meaningful experience. It's also important to understand that different psychedelics affect individuals in various ways—research the specific substance you plan to take to know what to expect. Read more about how set, setting, preparation and integration greatly influence the experience and your gains from it.
A sober, experienced individual to act as a trip sitter or guide can be an invaluable part of the psychedelic experience. This person’s role is to offer reassurance, monitor safety, and intervene if the trip becomes challenging. The guide should be someone you trust, who has their own experience with psychedelics, and who understands how to handle the emotional and psychological aspects of a psychedelic journey. Discuss any fears or needs with this person beforehand, ensuring that they are prepared to support you in any way necessary.
Never take psychedelics if you are on antidepressants or other mental health medications without consulting your healthcare provider. Additionally, avoid psychedelics if there is a history of psychosis or schizophrenia in your family. A responsible approach to psychedelics includes being honest with yourself and your healthcare provider about any mental health conditions that could affect your experience.
Psychedelics hold immense potential for personal growth, healing, and self-discovery, but they require a responsible and informed approach. By understanding the real risks, debunking myths, and taking appropriate safety precautions, individuals can navigate the psychedelic experience with greater confidence. Remember, preparation, mindset, and education are key to ensuring a safe and transformative journey.
Interested in a psychedelic retreat? See our program here. Just have some extra questions, feel welcome to ask them freely.
In de afgelopen jaren heeft het onderzoek naar en de verkenning van psychedelica een opmerkelijke heropleving gekend. Van onderzoeksinstellingen tot spirituele gemeenschappen worden deze stoffen erkend vanwege hun potentieel om transformerende ervaringen te katalyseren en psychologische genezing te bevorderen. Het veilige en nuttige gebruik van psychedelica berust echter op een fundamenteel begrip van drie belangrijke factoren: set, setting en dosering. Samen vormen ze de cruciale drie-eenheid voor een verantwoorde en zinvolle psychedelische ervaring. In deze blogpost gaan we in op het belang van elk element en onderzoeken we hoe ze de uitkomsten van psychedelische reizen beïnvloeden.
De "set" verwijst naar de mindset, verwachtingen en psychologische toestand van de persoon die aan een psychedelische reis begint. Het innerlijke landschap van een persoon speelt een cruciale rol in het vormgeven van de ervaring; het is van vitaal belang om openheid en respect voor de stoffen te cultiveren. Het omvat introspectie en zelfreflectie, het verduidelijken van je motivaties en het erkennen van angsten of zorgen die kunnen opkomen. Door psychedelica met een open, nieuwsgierige en ontvankelijke mindset te benaderen, kun je hun potentieel voor persoonlijke groei en inzicht vergroten.
Het concept van "setting" omvat de fysieke en sociale omgeving van de psychedelische ervaring. Het creëren van een veilige en ondersteunende setting is essentieel om de ervaring te optimaliseren en mogelijke risico's te beperken. De omgeving moet comfortabel zijn, de juiste muziek hebben, gedimde verlichting en toegang tot de natuur. Het is essentieel om een betrouwbare en ervaren gids te kiezen die een kalmerende aanwezigheid kan bieden en ondersteuning kan bieden indien nodig.
De dosering van een psychedelische stof speelt een cruciale rol in het bepalen van de intensiteit en duur van de ervaring. Een te hoge dosis kan eng worden, bovendien vinden de meeste voordelen plaats in het onderbewuste, waardoor het moeilijk kan zijn om de ervaring te herinneren. Een te lage dosis zorgt ervoor dat je de drempel van de reis niet overschrijdt en beperkte waarde uit de trip haalt.
In tegenstelling tot wat velen denken, heeft doseren weinig te maken met geslacht of lichaamsgewicht. Het hangt in plaats daarvan af van de wens om controle te houden en de starheid van de ego-structuur. Als iemand zich volledig kan overgeven, is de kans groter dat hij een volledige ervaring heeft met een lagere dosis.
Set, setting en dosering zijn geen op zichzelf staande factoren, maar zijn met elkaar verweven en werken samen om de algehele psychedelische ervaring vorm te geven. Bovendien is deze drie-eenheid niet vast, maar varieert voor elke persoon en elke reis. Factoren zoals persoonlijke intenties, mentale en fysieke gezondheid, en eerdere ervaringen met psychedelica moeten worden overwogen bij het afstemmen van de set, setting en dosering op elke unieke situatie.
Bij Awayk leggen we extra nadruk op onze voorbereidingsfase. Dit om ervoor te zorgen dat je begrijpt wat het betekent om te trippen, zodat je het met een positieve, open en zelfverzekerde mindset kunt benaderen. We zorgen voor een sterke basis van vertrouwen tussen jou en je gids, die de ervaring en energie heeft om je indien nodig te ondersteunen. En we bepalen de juiste dosering op basis van je vermogen om los te laten.
As the interest in natural psychedelics like magic mushrooms continues to rise, it’s crucial to address some of the common questions surrounding their use. One frequently searched topic is: Can you overdose on magic mushrooms?
Magic Mushrooms, known scientifically as psilocybin mushrooms, contain the psychoactive compound psilocybin. When ingested, psilocybin is converted into psilocin, which interacts with serotonin receptors in the brain, leading to altered perceptions, mood changes, and often profound psychological experiences. Earlier, we wrote a post on the myths and legitimate fears around Magic Mushrooms. Today, we would like to zoom in on following the specific question; can you overdose on shrooms?
Overdose:
Adverse Effects:
While the risk of a lethal overdose from magic mushrooms is minimal, the potential for severe psychological distress is real. Educating oneself and practising caution is key to minimising risks and ensuring a safer experience. For those looking to stay ahead of the curve and make informed decisions, understanding these nuances can be incredibly valuable. Want to know more about our psychedelic retreat? Just drop us a line.